University of Antwerp, Faculty of Medicine & Health Sciences, Laboratory of Experimental Medicine and Pediatrics (LEMP), Antwerp, Belgium; Department of Endocrinology, Diabetology & Metabolism, Antwerp University Hospital, Edegem, Belgium. Department of Cardiology, Antwerp University Hospital, Edegem, Belgium. University of Antwerp, Faculty of Medicine & Health Sciences, Laboratory of Experimental Medicine and Pediatrics (LEMP), Antwerp, Belgium. Department of Clinical Chemistry, Antwerp University Hospital, Edegem, Belgium. Department of Radiology, Antwerp University Hospital, Edegem, Belgium. University of Antwerp, Faculty of Medicine & Health Sciences, Laboratory of Experimental Medicine and Pediatrics (LEMP), Antwerp, Belgium; Department of Endocrinology, Diabetology & Metabolism, Antwerp University Hospital, Edegem, Belgium. Electronic address: luc.van.gaal@uza.be.